Endocrine Abstracts

Aims: Medullary thyroid carcinoma (MTC) is a rare endocrine cancer that accounts for approximately 5% of all thyroid cancers. Both the diagnosis and management of MTC could be difficult. Surgery is a main therapy in MTC, chemotherapy and external radiotherapy have limited efficacy. Recently, the relationship between some of the hemocytometer parameters and cancer has been investigated. In this study we aimed to determine the relationship between MTC and hemocytometer parameter...

Introduction: High thyroid hormone levels with unsupressed TSH (atypical hyperthyroxinemia) is one of the difficult endocrinologic conditions. When the conditions leading to euthyroid hyperthyoxinism are excluded, TSH secreting pituitary adenomas (TSHoma) and thyroid hormone resistance beta syndrome (THRB) lead to this picture as rare diseases. This report aims to evaluate the diagnostic and therapeutic stages in the case of TSH-secreting pituitary microadenoma which response ...

Background: Pituitary adenomas are usually benign epithelial tumors and they are the most common cause of sellar masses from the third decade on, accounting for up to 10% of all intracranial neoplasms. Pituitary adenomas typically present with neurologic symptoms, clinical findings of hormonal abnormalities or as an incidental finding on magnetic resonance imaging (MRI). Double pituitary adenomas are very rare, and they account for 1% of all pituitary adenomas in autopsy serie...

Objective: The prevalence of incidentally discovered papillary thyroid microcarcinoma (iPTMC) has increased with the expanded use of diagnostic imaging, including nuclear medicine imaging techniques. While iPTMC appears to have a better prognosis than non-incidental PTMC, it was suggested that thyroid carcinomas that were incidentally discovered during 18F-fluorodeoxyglucose positron emission tomography/computer tomography (FDG PET/CT) or parathyroid scintigraphy may have poor...

Background: In addition to glucose-lowering effects, Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) are the preferred treatment of choice in patients with heart failure due to their diuretic effects through glucosuria and natriuresis. However, there is limited data about urinary symptoms associated with SGLT2i use.Objectives: Low urinary tract symptoms such as increased urinary frequency, urgency, or incontinence due to SGLT2i use are not described i...

Background: The effects of gender-affirming hormonal therapy (GAHT) on body composition in transgender people assigned female at birth (AFAB) have been an area of interest. However, the impact of GAHT on muscle strength remains inadequately studied. We aimed to evaluate early alterations in muscle strength following GAHT in transgender people AFAB by isokinetic dynamometry, the gold standard for assessment of strength.Subjects and Methods: A total of 20 ...

Introduction: Myxoid adrenocortical adenoma was described by Brown et al. in 2000 (1). Myxoid adrenal cortical adenoma with pseudo glandular structure is a particular histological variant and is extremely rare. Accurate diagnosis is based on the combined evaluation of clinical features, adrenal imaging, and pathological features. Immunohistochemical studies (cytokeratin, melan-A, USP10, chromogranin, vimentin) can distinguish adrenocortical adenoma from other retroperitoneal m...

Background: Diabetic foot infections are an important cause of morbidity and mortality associated with poor glycemic control, polyneuropathy and micro/macrovascular diseases. The clinical, laboratory, radiological, pharmacological and/or surgical evaluation is required. We report a case of diabetic foot infection with bilaterally charcot joint.Case: A 52-year-old female patient with type 2 diabetes mellitus (DM), hypertension (HT), coronary artery diseas...

Introduction: Today, approximately 33% of the world population is either overweight or obese. National Health and Nutrition Examination Survey (NHANES) results show that, when 20 years and older American adults are examined, it is seen that 33% of them are overweight, 35.7% of them are obese, and 6.3% of them are morbidly obese (1). Roux-en-Y gastric bypass is a restrictive and malabsorptive combined method and is a complicated operation. Cases of endogenous hyperinsulinemic h...

Introduction: Amyloid goiter is a rare entity caused by massive amyloid infiltration of the thyroid gland. In some cases, differential diagnosis can be challenging. In this report, we present a patient with amyloid goiter caused by secondary amyloidosis.Case: A 48-year-old male patient was admitted to our hospital with the complaints of neck swelling, pain, and mild dysphagia that started three weeks after the SARS-Cov-2 infection and continued for one m...